Development of PPAR-agonist GW0742 as antidiabetic drug

The Effects PPAR Agonist GW0742 On Right Heart Hypertrophy gw0742

GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, μM and 2 μM for human PPARδ,

gw0742 GW0742 is a potent and highly selective PPARβδ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ  Chemicals & Biochemicals ; Supplier, APExBIO ; Notes, GW0742 is a synthetic, potent and selective PPAR-βδ agonist PPARs are ligand-dependent transcription GW0742 is a potent activator of PPARβδ receptors with EC50 concentrations in the low nM range Vascular relaxation induced by GW0742 of vessels was seen

ทดลองเล่นสล็อตฟรี 1000 GW0742 is a potent and highly selective PPARβδ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ